'Mice lacking both copies of the NPC1 gene, and therefore devoid of NPC1 protein, were completely resistant to infection.'
But he warned,jersey barcelona final rome, a downside of the discovery is the fact that the protein performs vital functions inside cells.
It transports cholesterol, and as such removing or disabling the protein can trigger severe illness. 
People who lack the protein due to genetic mutations develop a lethal neurodegenerative disorder called Niemann-Pick disease, which causes cells to become fatally clogged with cholesterol.
Yet,real madrid official jersey 13 14, the scientists believe that fact should not prove an insurmountable obstacle.
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This new study discovered the virus can only invade host cells by attaching to the protein - called Niemann-Pick C1 (NPC1). If it is unable to access that protein,arsenal goalkeeper jersey green, it loses the ability to infect and kill its victim

The disease ravaged parts of West Africa last year, infecting almost 27,netherlands home shirt 2013,000 people and killing more than 11,manchester united home shirt australia,000 - most in Sierra Leone,liverpool fc kit sponsor warrior, Guinea and Liberia
Co-author,france football shirt world cup 2014, Dr Andrew Herbert, from the US Army Medical Research Institute of Infectious Diseases, said: 'We think patients would be able to tolerate the treatment, which would be needed for only a short time.'
Totally blocking the protein and shutting out the virus permanently may not even be necessary, the researchers said.
The underlying story of an Ebola infection is that your immune system and the virus are in a race  Dr John Dye,arsenal away shirt jjb, of the US Army Medical Research Institute of Infectious DiseasesIn their study, 'knock-out' mice genetically modified to have no NPC1 were found to be completely protected against Ebola.
But those with one gene for the protein,buy germany football jersey india, instead of the normal two, also had a significant level of resistance against infection. 
Although the virus initially multiplied in their bodies,german hockey jersey for olympics, the attack was weak enough to be overcome by the body's immune system. 
Dr John Dye,brazil soccer jersey australia, another member of team, said: 'The underlying story of an Ebola infection is that your immune system and the virus are in a race. 
'If you can do anything to control the amount of virus that is in the system, keep it below a certain threshold,nike france away shirt 2013, your immune system in many cases will win that race.'
Of three NPC1-inhibiting drugs tested by the scientists on mice exposed to Ebola, only two provided a minimal level of protection.
However, the researchers hope more efficient ways of targeting NPC1 can be developed which could provide an effective treatment.相关的主题文章：


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